| | TABLE OF CONTENTS: Preface vii Contributors xi Chapter 1 The Structure and Biology of HIV 1: Introduction by Elana Cherry and Mark A. Wainberg Chapter 2 The Genetics of HIV-1 by Jon P. Anderson, Matthew Rain, Daniel Shriner, Allen G. Rodrigo, Yang Wang, David Nickle, Gerald H. Learn, Willscott E. Naugler, and James I. Mullins 44 Chapter 3 Nucleoside Inhibitors of HIV Reverse Transcriptase and the Problem of Drug Resistance by Matthias Gdtte, Shalom Spira, and Mark A. Wainberg 100 Chapter 4 Non-Nucleoside Reverse Transcriptase Inhibitors of HIV-1 by Jan Balzarini 132 Chapter 5 HIV -1 Protease Inhibitors by Jon H. Condra and Joseph P. Vacca 172 Chapter 6 The Biology and Biochemistry of Integration as a Target for Chemotherapeutic Intervention by Daria J. Hazuda 223 Chapter 7 Chemokine Receptors in HIV Infection and AIDS by Nathaniel R. Landau 250 Chapter 8 Novel HIV-1 Therapeutic Targets: Regulatory Functions by Catherine Ulich and Richard B. Gaynor 294 Chapter 9 Novel HIV -1 Therapeutic Targets: Accessory Functions by Mario Stevenson 328 Chapter 10 The Interface between the Pathogenesis and Treatment of HIV Infection by Mark B. Feinberg 384 Chapter 11 HIV Prevention: Implementing Proven Prevention Interventions to Control the Global Epidemic by Chris Collins, Todd Summers, and Tom Coates 441 Chapter 12 The Immunobiology of HIV -1 Infection by Norman L. Letvin 459 Chapter 13 HIV Vaccines 2000: Prospects and Challenges by Spyros A. Kalams and Bruce D. Walker 481 Index 511
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