Exploitation and Developing Countries:
The Ethics of Clinical Research
Edited by Jennifer S. Hawkins & Ezekiel J. Emanuel

Paper | 2008 | $24.95 / £14.95
Cloth | 2008 | $65.00 / £38.95
336 pp. | 6 x 9 | 2 tables.

Shopping Cart | Endorsements | Table of Contents
Introduction [HTML] or [PDF]

When is clinical research in developing countries exploitation? Exploitation is a concept in ordinary moral thought that has not often been analyzed outside the Marxist tradition. Yet it is commonly used to describe interactions that seem morally suspect in some way. A case in point is clinical research sponsored by developed countries and carried out in developing countries, with participants who are poor and sick, and lack education. Such individuals seem vulnerable to abuse. But does this, by itself, make such research exploitative?

Exploitation and Developing Countries is an attempt by philosophers and bioethicists to reflect on the meaning of exploitation, to ask whether and when clinical research in developing countries counts as exploitative, and to consider what can be done to minimize the possibility of exploitation in such circumstances. These reflections should interest clinical researchers, since locating the line between appropriate and inappropriate use of subjects--the line between exploitation and fair use--is the central question at the heart of research ethics. Reflection on this rich and important moral concept should also interest normative moral philosophers of a non-Marxist bent.

In addition to the editors, the contributors are Richard J. Arneson, Alisa L. Carse, Margaret Olivia Little, Thomas Pogge, Andrew W. Siegel, and Alan Wertheimer.

Jennifer S. Hawkins is assistant professor of philosophy at the University of Toronto. Ezekiel J. Emanuel is chairman of the Department of Bioethics at the Clinical Center of the National Institutes of Health.

Endorsements:

"This is an outstanding contribution to the growing literature on the ethics of research with human subjects, and a fine example of what bioethics can offer at its best. Anyone with a serious interest in these issues will need to read this book from start to finish."--Daniel Wikler, Harvard School of Public Health

"This book contributes significantly to the literature on exploitation in clinical research conducted in the developing world."--Patricia Marshall, Case Western Reserve University

Table of Contents:

Introduction: Why Exploitation? by Jennifer S. Hawkins and Ezekiel J. Emanuel 1
CHAPTER 1: Research Ethics, Developing Countries, and Exploitation: A Primer by Jennifer S. Hawkins 21
CHAPTER 2: Case Studies: The Havrix Trial and the Surfaxin Trial 55
CHAPTER 3: Exploitation in Clinical Research by Alan Wertheimer 63
CHAPTER 4: Testing Our Drugs on the Poor Abroad by Thomas Pogge 105
CHAPTER 5: Broadly Utilitarian Theories of Exploitation and Multinational Clinical Research by Richard J. Arneson 142
CHAPTER 6: Kantian Ethics, Exploitation, and Multinational Clinical Trials by Andrew W. Siegel 175
CHAPTER 7: Exploitation and the Enterprise of Medical Research by Alisa L. Carse and Margaret Olivia Little 206
CHAPTER 8: Exploitation and Placebo Controls by Jennifer S. Hawkins 246
CHAPTER 9: Addressing Exploitation: Reasonable Availability versus Fair Benefits by Ezekiel J. Emanuel 286
Index 315

Subject Areas:

• Philosophy
• Biological Sciences

Shopping Cart:

For customers in the U.S., Canada, Latin America, Asia, and Australia
Paper: $24.95 ISBN13: 978-0-691-12676-0
Cloth: $65.00 ISBN13: 978-0-691-12675-3

For customers in Europe, Africa, the Middle East, and India
Paper: £14.95 ISBN13: 978-0-691-12676-0
Cloth: £38.95 ISBN13: 978-0-691-12675-3

Prices subject to change without notice

File created: 8/22/2008

Questions and comments to: webmaster@press.princeton.edu
Princeton University Press